| District 4 |
| |
| Team | Mascot | Years |
| |
| Athens | Wildcats | 1900 - |
| Benton | Tigers | 1921 - 1931 |
| Bloomsburg | Panthers | 1899 - |
| Bucktail | Bucks | 1927 - |
| Canton | Warriors | 1921 - |
| Catawissa | Bears | 1899 - 1932 |
| Central Columbia | Blue Jays | 1960 - |
| Coal Township | Purple Demons | 1923 - 1964 |
| Columbia Montour Vo-Tech | Rams | 1972 - |
| Conyngham Township | Mounties | 1931 - 1935 |
| Cowanesque Valley | Indians | 1963 - 2000 |
| Danville | Ironmen | 1900 - |
| East Juniata | Tigers | 1967 - |
| Galeton | Tigers | 1916 - 1933 |
| Hughesville | Spartans | 1926 - |
| Jersey Shore | Bulldogs | 1901 - |
| Kulpmont | Wildcats | 1930 - 1963 |
| Lewisburg | Green Dragons | 1904 - |
| Line Mountain | Eagles | 1966 - |
| Lourdes Regional | Red Raiders | 1956 - |
| Loyalsock | Lancers | 1960 - |
| Mahanoy Joint | Bruins | 1949 - 1965 |
| Mansfield | Tigers | 1919 - 1928 |
| Mifflinburg | Wildcats | 1905 - |
| Millville | Quakers | 1924 - 1929 |
| Milton | Black Panthers | 1899 - |
| Montgomery | Red Raiders | 1903 - |
| Montoursville | Warriors | 1930 - |
| Mount Carmel | Red Tornadoes | 1893 - |
| Mount Carmel Catholic | Rams | 1932 - 1963 |
| Mount Carmel Township | Golden Bears | 1920 - 1951 |
| Muncy | Indians | 1904 - |
| Nescopeck | Warriors | 1909 - 1964 |
| North Penn (Blossburg) | Panthers | 1912 - |
| Northumberland | Pineknotters | 1893 - 1964 |
| Picture Rocks | Rockets | 1924 - 1935 |
| Ralston | Jack Rabbits | 1931 - 1947 |
| Sayre | Redskins | 1905 - |
| Scott Township | Bluejays | 1908 - 1924 |
| Selinsgrove | Seals | 1926 - |
| Shamokin | Indians | 1895 - |
| Shikellamy | Braves | 1965 - |
| South Williamsport | Mounties | 1927 - |
| Southern Columbia | Tigers | 1963 - |
| Sunbury | Owls | 1893 - 1964 |
| Sunbury IOOF Orphanage | Red Raiders | 1930 - 1937 |
| Towanda | Knights | 1900 - |
| Trevorton | Red Devils | 1923 - 1965 |
| Troy | Trojans | 1921 - |
| Warrior Run | Defenders | 1901 - |
| Wellsboro | Green Hornets | 1911 - |
| Williamsport | Millionaires | 1892 - |
| Williamsport Saint Josephs | Irish | 1931 - 1942 |
| Williamsport Saint Marys | Dutch | 1927 - 1932 |
| Wyalusing | Rams | 1956 - |
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